Cat#:PA-3498F;Product Name:Rabbit Anti-Human p27 Tumor Suppression Protein Antibody;Synonym:P27; p27 Tumor Suppression Protein; CDKN1B;Background:This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.;Description:Rabbit Anti-Human p27 Tumor Suppression Protein Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1, kappa;Application:IP, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Rabbit Anti-Human p27 Tumor Suppression Protein Antibody
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Cat#:
PA-3498F
Product Name:
Rabbit Anti-Human p27 Tumor Suppression Protein Antibody
Synonym:
P27; p27 Tumor Suppression Protein; CDKN1B
Gene Introduction:
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
Description:
Rabbit Anti-Human p27 Tumor Suppression Protein Polyclonal Antibody
Host Species:
Rabbit
Species Reactivity:
Human
Isotype:
IgG1, kappa
Application:
IP, WB
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles