Cat#:PA-1305F;Product Name:Mouse Anti-Human MME Antibody, RPE-Conjugated;Synonym:MME; atriopeptidase; Atriopeptidase; CALLA; CD10; common acute lymphocytic leukemia antigen; Common acute lymphocytic leukemia antigen; DKFZp686O16152; EC 3.4.24.11; EC 3.4.24; enkephalinase; Enkephalinase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase); membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; membrane metallo-endopeptidase; MGC126681; MGC126707; NEP; neprilysin; Neprilysin; neutral endopeptidase 24.11; Neutral endopeptidase 24.11; OTTHUMP00000212961; OTTHUMP00000212963; OTTHUMP00000212964; OTTHUMP00000212965; OTTHUMP00000212966; SFE; skin fibroblast elastase; Skin fibroblast elastase;Background:MME is a 100 kDa protein belonging to a family of type II transmembrane metalloproteases which also includes the leukocyte antigens CD13, CD26, CD73 and aminopeptidase. The gene encoding MME is located on chromosome 3. MME is a zinc-dependent enzyme and is thought to down-regulate cellular responses to peptide hormones. On lymphoid cells, MME is expressed on immature T and B precursor cells but is lost as the cells reach maturation. MME is, however, re-expressed on proliferating B cells and mature neutrophils. Anti- MME, was included in the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with MME.;Description:Mouse Anti-Human MME Monoclonal Antibody, RPE-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:SS2/47;Isotype:IgG1, kappa;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;