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Recombinant Human TNFRSF12A / FN14 / TWEAKR Protein (Fc Tag) Online Inquiry

Product Name:Recombinant Human TNFRSF12A / FN14 / TWEAKR Protein (Fc Tag)
Synonym: FN14; CD266; TWEAKR; TNF receptor superfamily member 12A; FGF-inducible 14; fibroblast growth factor-inducible immediate-early response protein 14; tweak-receptor; type I transmembrane protein Fn14
Gene Introduction: TNFRSF12A, the full name is TNF receptor superfamily member 12A. Gene ID is 51330. Tumor necrosis factor receptor superfamily member 12A also known as the TWEAK receptor (TWEAKR) is a protein that in humans is encoded by the TNFRSF12A gene.
Description: A DNA sequence encoding the human TNFRSF12A isoform 1 (Q9NP84-1) extracellular domain (Glu 28-Trp 79) was fused with the Fc region of human IgG1 at the N-terminus.
Source: Human Cells
Predicted N Terminal: Glu
AA Sequence: Glu 28-Trp 79
Molecular Characterization: The recombinant human TNFRSF12A protien is a disulfide-linked homodimeric protein. The reduced monomer consists of 313aa and has a calculated molecular weight of 34 kDa. The apparent molecular mass of TNFRSF12A/Fc monomer is approximately 37 kDa in SDS-PAGE under reducing conditions.
Purity: Greater than 95% as determined by SDS-PAGE
Endotoxin: < 1.0 EU per ug of the TNFRSF12A protein as determined by the LAL method
Bioactivity: Please contact us for detailed information
Formulation: Recombinant human TNFRSF12A was lyophilized from sterile PBS, pH 7.4
Stability: Recombinant TNFRSF12A Proteins are stable for up to 1 year from date of receipt at -70℃
Reconstitution: Please see related COA for specific instructions.
Host Species: Human
Storage: Avoid repeated freeze-thaw cycles. In lyophilized state for 1 year (4-8℃); Upon reconstitution under sterile conditions for 2 weeks (4-8℃) or 3 months (-20℃ to -70℃).
References: Knockdown of the differentially expressed gene TNFRSF12A inhibits hepatocellular carcinoma cell proliferation and migration in vitro. Wang T, et al. Mol Med Rep, 2017 Mar. PMID 28138696

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