Cat#:PA-220F;Product Name:Sheep Anti-Rabbit Tissue Plasminogen Activator (tPA) Antibody;Synonym:DKFZp686I03148; Plasminogen activator tissue; Plasminogen activator tissue type; Plasminogen Activator Tissue Type Isoform 1 Preproprotein; t PA; T Plasminogen Activator; t-PA; Tissue plasminogen activator (t PA); Tissue-type plasminogen activator chain B; TPA_HUMAN; TPA1; PLAT; plasminogen activator, tissue; TPA; T-PA; DKFZp686I03148; tissue-type plasminogen activator; alteplase; reteplase; OTTHUMP00000225783; OTTHUMP00000225784; OTTHUMP00000225785; OTTHUMP00000225786; OTTHUMP00000225787; OTTHUMP00000225788; t-plasminogen activator;Background:Tissue plasminogen activator (abbreviated TPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown. Because it works on the clotting system, tPA is used in clinical medicine to treat only embolic or thrombotic stroke. Use is contraindicated in hemorrhagic stroke and head trauma.;Description:Sheep Anti-Rabbit Tissue Plasminogen Activator (tPA) Polyclonal Antibody;Host Species:Sheep;Species Reactivity:Rabbit;Isotype:IgG2a;Application:ELISA, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Tissue plasminogen activator (abbreviated TPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown. Because it works on the clotting system, tPA is used in clinical medicine to treat only embolic or thrombotic stroke. Use is contraindicated in hemorrhagic stroke and head trauma.