Cat#:PA-1652F;Product Name:Rat Anti-Mouse CD11b (MAC-1) Antibody;Synonym:CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; mgC 117044; ITGAM; integrin alpha-M; CR-3 alpha chain; antigen CD11b (p170); leukocyte adhesion receptor MO1; CD11 antigen-like family member B; macrophage antigen alpha polypeptide; cell surface glycoprotein MAC-1 subunit alpha; neutrophil adherence receptor alpha-M subunit;Background:This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.;Description:Rat Anti-Mouse CD11b (MAC-1) Monoclonal Antibody;Host Species:Rat;Species Reactivity:Mouse;Clone#:M2/82;Isotype:IgG2b (Rat);Application:EIA, Pr;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;