Cat#:PA-1503F;Product Name:Rabbit Anti-L-dopa Antibody;Synonym:L-dopa; 3 4 dihydroxy L phenylalanine; L dihydroxyphenylalanine; Levodopa; BETA-(3,4-DIHYDROXYPHENYL)-L-ALANINE;HYDROXYTYROSINE;H-PHE(3,4-DI-HYDROXY)-OH;H-PHE(3,4-DI-OH)-OH;H-TYR(3-HYDROXY)-OH;L-BETA-(3,4-DIHYDROXYPHENYL)ALANINE;L-DOPA;L-DOPA, L-3-HYDROXYTYROSINE;Background:L Dopa is an intermediate in dopamine biosynthesis. Clinically, L Dopa is used in the management of Parkinson's disease. It is used as a prodrug to increase dopamine levels since it is able to cross the blood-brain barrier whereas dopamine itself cannot. Once L Dopa has entered the central nervous system (CNS), it is metabolised to dopamine by aromatic L amino acid decarboxylase. This also occurs in the peripheral tissues, causing adverse effects and decreasing the available dopamine to the CNS, so it is standard practice to co administer a peripheral DOPA decarboxylase inhibitor and often a catechol-O-methyl transferase (COMT) inhibitor.;Description:Rabbit Anti-L-dopa Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:N/A;Isotype:IgG1a;Application:ELISA, LF;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;