Cat#:PA-779F;Product Name:Rabbit Anti-Human PTCH2 (amino acids 226–235) Antibody;Synonym:PTC2; PTCH2; Patched Tumor Suppressor 2; protein patched homolog 2; protein patched homolog 2; patched homolog 2; OTTHUMP00000010158;Background:This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described.;Description:Rabbit Anti-Human PTCH2 (amino acids 226–235) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
PTC2; PTCH2; Patched Tumor Suppressor 2; protein patched homolog 2; protein patched homolog 2; patched homolog 2; OTTHUMP00000010158
Gene Introduction:
This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described.