Cat#:PA-3507F;Product Name:Rabbit Anti-Human CDH13 Antibody;Synonym:CDH13; cadherin 13, H-cadherin (heart); CDHH; P105; cadherin-13; T-cad; H-cadherin; T-cadherin; heart cadherin; truncated-cadherin;Background:This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.;Description:Rabbit Anti-Human CDH13 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1, kappa;Application:WB, IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description:
Rabbit Anti-Human CDH13 Polyclonal Antibody
Host Species:
Rabbit
Species Reactivity:
Human
Isotype:
IgG1, kappa
Application:
WB, IHC
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles