Cat#:PA-3678F;Product Name:Rabbit Anti-Human CASP7 (N-terminal) Antibody;Synonym:CASP7; Apoptotic protease Mch3; CASP 7; Caspase 7 subunit p11; Caspase 7 subunit p20; CMH1; ICE LAP3; ICE like apoptotic protease 3; OTTHUMP00000020510; OTTHUMP00000020511; OTTHUMP00000020512; OTTHUMP00000020513; OTTHUMP00000020514; Lice2 alpha/beta/gamma; caspase 7 isoform delta; caspase 7, apoptosis-related cysteine protease; caspase 7, apoptosis-related cysteine peptidase; MCH3; CMH-1; ICE-LAP3; EC 3.4.22.60; EC 3.4.22;Background:This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.;Description:Rabbit Anti-Human CASP7 (N-terminal) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.