Cat#:PA-3679F;Product Name:Rabbit Anti-Human CASP6 (N-terminal) Antibody;Synonym:CASP6; Apoptosis Related Cysteine Protease; Apoptotic cysteine protease MCH2; Apoptotic protease MCH 2; Apoptotic protease Mch-2; OTTHUMP00000162742; OTTHUMP00000162743; apoptotic protease MCH-2; caspase 6, apoptosis-related cysteine protease; caspase-6; MCH2; Mch 2; Human cysteine protease Mch2 isoform alpha; EC 3.4.22.59; EC 3.4.22;Background:This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.;Description:Rabbit Anti-Human CASP6 (N-terminal) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;