Cat#:PA-883F;Product Name:Mouse Anti-Mouse Plaur Antibody;Synonym:ATF; ATF uPA; Plasminogen activator; Plasminogen activator urinary; Plasminogen activator urokinase; PLAU; u PA; U plasminogen activator; U-plasminogen activator; UPA; URK; UROK_HUMAN; Urokinase plasminogen activator; Urokinase type plasminogen activator; Urokinase type plasminogen activator precursor; Urokinase-type plasminogen activator chain B;Background:Urokinase (trade name Abbokinase), also called urokinase-type plasminogen activator (uPA), is a serine protease (EC 3.4.21.73). Urokinase was originally isolated from human urine, but is present in several physiological locations, such as blood stream and the extracellular matrix. The primary physiological substrate is plasminogen, which is an inactive zymogen form of the serine protease plasmin. Activation of plasmin triggers a proteolysis cascade that, depending on the physiological environment, participates in thrombolysis or extracellular matrix degradation. This links urokinase to vascular diseases and cancer.;Description:Mouse Anti-Mouse Plaur Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Mouse;Clone#:B044N;Isotype:IgG1, K;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;