Cat#:PA-1319F;Product Name:Mouse Anti-Microphthalmia Transcription Factor (MiTF) Antibody;Synonym:MITF; microphthalmia-associated transcription factor; Microphthalmia Transcription Factor; MI; WS2; WS2A; bHLHe32; Class E basic helix-loop-helix protein 32; bHLHe32;Background:This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.;Description:Mouse Anti-Microphthalmia Transcription Factor (MiTF) Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:34CB6;Isotype:IgG1/kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;