Cat#:PA-097F;Product Name:Mouse Anti-Human Vimentin Antibody;Synonym:VIM; FLJ36605; Vimentin; vimentin; OTTHUMP00000019225; OTTHUMP00000019224;Background:Vimentin is a 55 kDa intermediate filament (IF) protein, which form part of the cytoskeleton of vertebrate cells. Among the five classes* of IFs vimentin belongs to class III and is expressed in the cytoplasma of cells of mesenchymal origin. Being the predominant IF protein in mesenchymal cells vimentin was initially believed to be a useful marker for distinguishing non-epithelial from epithelial derived nepolasms. The co-expression of intermediate filaments, particularly vimentin and cytokeratin, has now been demonstrated in a variety of normal cells/tissues and in neoplastic lesions, necessitating the use of a panel of antibodies in differential tumour diagnosis. Recently, an additional class (i.e. class VI) was created for nestin.;Description:Mouse Anti-Human Vimentin Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:Vim 3C5;Isotype:IgG2a, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Vimentin is a 55 kDa intermediate filament (IF) protein, which form part of the cytoskeleton of vertebrate cells. Among the five classes* of IFs vimentin belongs to class III and is expressed in the cytoplasma of cells of mesenchymal origin. Being the predominant IF protein in mesenchymal cells vimentin was initially believed to be a useful marker for distinguishing non-epithelial from epithelial derived nepolasms. The co-expression of intermediate filaments, particularly vimentin and cytokeratin, has now been demonstrated in a variety of normal cells/tissues and in neoplastic lesions, necessitating the use of a panel of antibodies in differential tumour diagnosis. Recently, an additional class (i.e. class VI) was created for nestin.
Description:
Mouse Anti-Human Vimentin Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Human
Clone#:
Vim 3C5
Isotype:
IgG2a, kappa
Application:
IHC
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles