Cat#:PA-096F;Product Name:Mouse Anti-Human Vimentin Antibody;Synonym:VIM; FLJ36605; Vimentin; vimentin; OTTHUMP00000019225; OTTHUMP00000019224;Background:Vimentin is a 57 kDa intermediate filament (IF) protein, which form part of the cytoskeleton of vertebrate cells. Among the five classes of IFs, comprising nine groups, vimentin belongs to class III, showing a high degree of specificity for cells of mesenchymal origin. The cell type specificity, displayed by each of the IF subtypes, was initially thought to be retained in malignant cells as well as their normal counterpart, which made IFs important as diagnostic markers in histogenesis. The coexpression of intermediate filaments, particularly vimentin and cytokeratin, has now been demonstrated in a variety of normal cells/tissues and in neoplastic lesions, necessitating the use of a panel of antibodies in differential tumour diagnosis. Recently, an additional class (i.e. class VI) was created for nestin.;Description:Mouse Anti-Human Vimentin Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:W0;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;