Cat#:PA-320F;Product Name:Mouse Anti-Human TIA1 Antibody;Synonym:TIA1; TIA1 cytotoxic granule-associated RNA binding protein; TIA-1; nucleolysin TIA-1 isoform p40; T-cell-restricted intracellular antigen-1; Nucleolysin TIA-1 isoform p40; RNA-binding protein TIA-1; p40-TIA-1; OTTHUMP00000160046; OTTHUMP00000160047; OTTHUMP00000204010; OTTHUMP00000204044; p40-TIA-1 (containing p15-TIA-1); cytotoxic granule-associated RNA-binding protein; TIA1 cytotoxic granule-associated RNA-binding protein;Background:The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.;Description:Mouse Anti-Human TIA1 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:2G9A10G6;Isotype:IgG1,k;Application:EIA, IEP;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Description:
Mouse Anti-Human TIA1 Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Human
Clone#:
2G9A10G6
Isotype:
IgG1,k
Application:
EIA, IEP
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles