Cat#:PA-460F;Product Name:Mouse Anti-Human STAT6 Antibody;Synonym:STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6; signal transducer and activator of transcription 6; STAT, interleukin4-induced; transcription factor IL-4 STAT;Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.;Description:Mouse Anti-Human STAT6 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:16000000000011;Isotype:IgG1;Application:ELISA, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;