Cat#:PA-776F;Product Name:Mouse Anti-Human PTGS1 Antibody;Synonym:COX1; PTGS1; PTGHS; Prostaglandin H2 synthase 1; PCOX1; PGHS1; COX3; PGG/HS; COX-1; PHS 1; Prostaglandin-endoperoxide synthase 1; EC 1.14.99.1; Cyclooxygenase-1; PGHS-1; PGH synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase;Background:Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandinbiosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodesPTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugssuch as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts isdifferentially regulated by relevant cytokines and growth factors.;Description:Mouse Anti-Human PTGS1 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Bovine;Clone#:CYO-2;Isotype:IgG2b;Application:ELISA, IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;