Cat#:PA-2925F;Product Name:Mouse Anti-Human Factor IX Antibody;Synonym:FIX; P19; PTC; HEMB; coagulation factor IX; F9 p22; FIX F9; factor 9; factor IX F9; serine protease; Christmas factor; plasma thromboplastic component ; plasma thromboplastin component; coagulation factor IX; EC 3.4.21; EC 3.4.21.22; OTTHUMP00000024154; MGC129642; MGC129641; F9;Background:Factor IX circulates in the blood as an inactive zymogen at the normal concentration of approximately 3 µg/ml. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca2+ ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X linked disorder, also called hemophilia B or Christmas disease. The disease affects approximately 1 in 50, 000 of the population (almost exclusively males).;Description:Mouse Anti-Human Factor IX Monoclonal Antibody;Host Species:Mouse;Species Reactivity:human, bovine, rabbit, sheep, porcine and canine;Clone#:AHIX-5052;Isotype:IgG1;Application:RIA, Blot, ELISA, IHC, purification;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;