Cat#:PA-3630F;Product Name:Mouse Anti-Human CD19 Molecule Antibody, APC-Conjugated;Synonym:CD19; CD19 molecule; CD19 antigen; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD_antigen=CD19; B4; CVID3; MGC12802; OTTHUMP00000122551;Background:CD19 is a 120 kDa transmembrane glycoprotein with a reduced Mr of 95000. CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains, and it is a critical signal transduction molecule that regulates B lymphocytedevelopment, activation, and differentiation. CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes. The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differ rentiation to plasma cells.;Description:Mouse Anti-Human CD19 Molecule Monoclonal Antibody, APC-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:HD48;Isotype:IgG1, kappa;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;