Cat#:PA-3222F;Product Name:Monoclonal Mouse Anti-Human Cytokeratin 5 / 6;Synonym:58 kDa cytokeratin; CK5; Cytokeratin 5; Cytokeratin 6A; Cytokeratin 6B; DDD; EBS2; K5; K6A; K6B; Keratin 5; Keratin 6 alpha; Keratin 6A; Keratin 6B; Keratin type II cytoskeletal 5; KRT 5; KRT 5A; KRT 6A; KRT 6B;Background:Cytokeratins are alpha-type fibrous polypeptides with a diameter of 7-11 nm. They are important components of the cytoskeleton in almost all epithelial cells as well as in some non-epithelial cell types. Cytokeratins are, generally, held to be the most ubiquitous markers of epithelial differentiation, and, so far, 20 distinct types numbered by Moll have been revealed. The CK 5 is a high molecular weight, basic type of cytokeratin, with a molecular mass of 58 kDa, expressed in the basal, the intermediate and the superficial cell layers of stratified epithelia as well as in transitional epithelia, complex epithelia, and in mesothelial cells and mesothelioma. CK 5 has not, with few exceptions, been found in simple epithelia and in non-epithelial cells. CK 6 is also a high molecular weight, basic type of cytokeratin, with a molecular mass of 56 kDa, expressed by proliferating squamous epithelium often paired with CK 16 (48 kDa);Description:Monoclonal Mouse Anti-Human Cytokeratin 5/6;Host Species:Mouse;Species Reactivity:Human;Clone#:D5/16 C5;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;