Cat#:RP-1463HAT;Product Name:Recombinant Human HtrA2 / Omi Protein;Synonym:High temperature requirement protein A2;Description:HtrA2/Omi is a mammalian serine protease at high temperatures and has a chaperone activity at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. Mature form of HtrA2/Omi(residues 134-458) was overproduced in E.coli,. This recombinant protein was purified using the column chromatography techniques.;Source:E.coli;AA Sequence:134-458aa;Molecular Characterization:36kDa;Purity:Greater than 95% by SDS-PAGE;Formulation:Liquid Solution;Stability:Recombinant Human HtrA2/Omi Protein was stable up to 1 year from date of receipt at -70℃;Concentration:0.5mg/mL;Storage Buffer:Recombinant Human HtrA2/Omi protein was supplied in 20 mM Tris-HCl buffer (pH 8.0), 50 mM NaCl, 1 mM DTT, 20% Glycerol;Storage:Recombinant Human HtrA2/Omi Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;