Cat#:RP-952HAT;Product Name:Recombinant Human EGFR Protein;Synonym:Epidermal growth factor receptor;Background:Gene ID: 1956. EGFR, the full name is epidermal growth factor receptor. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016];Description:The human recombinant EGFR, fused with hIgG-His tag at C-terminus, was produced in CHO cell. This recombinant protein was purified using our unique purification methods.;Source:CHO cells;AA Sequence:25-645aa;Molecular Characterization:95.5kDa;Purity:Greater than 90% by SDS-PAGE;Endotoxin:< 1.0 EU per ug of protein as determined by LAL method.;Formulation:Liquid Solution;Stability:Recombinant Human EGFR Protein was stable up to 1 year from date of receipt at -70℃;Host Species:Human;Concentration:0.25mg/mL;Storage Buffer:Recombinant Human EGFR protein was supplied in PBS (pH 7.4) containing 10% glycerol.;Storage:Recombinant Human EGFR Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;References:Prognostic implication of EGFR gene mutations and histological classification in patients with resected stage I lung adenocarcinoma. Lin CY, et al. PLoS One, 2017. PMID 29065153;