Cat#: | RP-447AC |
Product Name: | Biotinylated Recombinant Human EGFR, His Tag & Avi Tag |
Synonym: | EGFR,ERBB,ERBB1,HER1,PIG61,mENA |
Gene Introduction: | Gene ID: 1956. EGFR, the full name is epidermal growth factor receptor. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016] |
Description: | Biotinylated recombinant Human EGFR protein with His Tag is produced in HEK293 cells. |
Source: | HEK293 |
Predicted N Terminal: | Leu 25 |
Purity: | Greater than 90% as determined by SDS-PAGE. |
Endotoxin: | < 1.0 EU per μg of Biotinylated Recombinant Human EGFR, His Tag & Avi Tagby the LAL method. |
Formulation: | Biotinylated Recombinant Human EGFR, His Tag & Avi Tag was lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.Contact us for customized product form or formulation. |
Stability: | Biotinylated Recombinant Human EGFR, His Tag & Avi Tag was stable up to 1 year from date of receipt at -70℃ |
Host Species: | Human |
Usage: | For Lab Research Use Only |
Storage: | Store Biotinylated Recombinant Human EGFR, His Tag & Avi Tag under sterile conditions at -20℃ to -80℃. It is recommended that the recombinant protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
References: | Osimertinib in Untreated EGFR-Mutated Advanced Non–Small-Cell Lung Cancer,N Engl J Med 2018; 378:192-193 DOI: 10.1056/NEJMe1714580 |