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Recombinant Human EGFR Protein(Strep Tag) Online Inquiry

Product Name:Recombinant Human EGFR Protein(Strep Tag)
Gene Introduction: Gene ID: 1956. EGFR, the full name is epidermal growth factor receptor. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Description: Human EGF R with Strep Tag is produced in HEK293 cells. It contains AA Leu 25 - Ser 645.
Source: HEK293
Predicted N Terminal: Leu 25
AA Sequence: Leu 25 - Ser 645.
Molecular Characterization: Recombinant Human EGFR Protein has a calculated MW of 76.1 kDa. The recombinant protein migrates as 110-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: Greater than 95% as determined by SDS-PAGE.
Endotoxin: < 1.0 EU per μg of recombinant human EGFR protein by the LAL method.
Formulation: Recombinant human EGFR protein was lyophilized from 0.22 μm filtered solution in PBS, pH7.4.
Stability: Recombinant human EGFR protein was stable up to 1 year from date of receipt at -70℃
Host Species: Human
Usage: For Lab Research Use Only
Storage: Store recombinant human EGFR protein under sterile conditions at -20℃ to -80℃. It is recommended that the recombinant protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
References: Prognostic implication of EGFR gene mutations and histological classification in patients with resected stage I lung adenocarcinoma. Lin CY, et al. PLoS One, 2017. PMID 29065153

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