Cat#:EIA-623C;Product Name:HSV-2 IgG ELISA Kit;Size:96;Sample:serum or plasma;Intended use:IVD;Synonym:HSV; HSV-2;Herpes simplex virus; HSV epitope; QPELAPEDPED; HSV epitope tag; Group I (dsDNA); Herpesviridae; Alphaherpesvirinae; Simplexvirus;Background:Herpes Simplex virus is a widespread human pathogen. An HSV infection usually causes subclinic manifestations. However, it may develop generalised and fatal infection as in new-borns and immunocompromised people.1 Two types of HSV are serologically distinguishable: HSV-1 and HSV-2. Both of them present biological as well as epidemiological differences. Although both viruses infect epithelial cells, HSV-1 is normally associated with oral infections and lesions above waist and HSV-2 is associated with genital infections and lesions below waist. However, a recognisable but variable proportion of genital infection is attributable to HSV-1, and the distinction in virus type is important as genital HSV-1 infections are not as clinically severe and are less prone to recur. Because of the strong serological cross-reactivity between HSV-1 and HSV-2, type-specific serological diagnosis has been technically very difficult. Nevertheless, the use of the purified HSV-2 glycoprotein G (gG2) allows to determine only HSV-2 type specific antibodies.2,3 The screening of all pregnant women and their sexual partners for HSV-2 antibodies would help to prevent primary maternal infections. It would also help to identify all women at risk for recurrent HSV-2 infection as well as asymptomatic HSV-2 seropositive mothers4,5 and to prevent neonatal infection.;Species Reactivity:Virus;Application:qualitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:I-ELISA;