Cat#:EIA-664C;Product Name:Hantavirus Dobrava / Hantaan IgG / IgM ELISA Kit;Size:96 T;Sample:Human serum;Intended use:IVD;Synonym:Hantavirus; Hantavirus Dobrava; Hantavirus Hantaan; Dobrava; Hantaan; Group V ((-)ssRNA); Unassigned; Bunyaviridae;Background:Hantaviruses are single-stranded enveloped RNA viruses in the Bunyaviridae family, are widespread and are strictly associated with their serotype-specific reservoir hosts. They cause hemorrhagic fever with renal syndrome (HFRS) in Europe and Asia and lead to hantavirus cardiopulmonary syndrome (HCPS) in America. The severity of the disease depends on the infecting virotype with case fatality rates from 0.1% -10% for HFRS and 25-35% for HCPS. Natural reservoir hosts are rodents, the virus is transmitted to humans via aerosol derived from rodent urine, feces or saliva. HFRS is caused by Hantaan virus and the closely related Dobrava virus as well as Seoul type and Puumala virus. Hantavirus serotypes show the same geographical distribution pattern as their reservoir hosts. Hantaan virus (host: Apodemus agrarius) is endemic in Asia, Dobrava virus (hosts: different Apodemus sp.) is distributed in the Balkans, Central, Eastern and Southern Europe, the form of the disease ranges from moderate to severe. Puumala serotype (host: Myodes clareolus) is predominant in Scandinavia and Western Europe and causes a mild infection, also called Nephropathia epidemica (NE). In Germany more than 90% of Hantavirus infections are caused by Puumala Virus. People at high risk are farmers, soldiers, campers.;Species Reactivity:Virus;Application:Qualitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:I-ELISA;