Cat#:PA-821F;Product Name:Western Immunoblotting Reagents for Protein Kinase C Theta;Synonym:PRKCQ; protein kinase C, theta; PRKCT; MGC126514; MGC141919; nPKC-theta; Protein kinase C theta type; EC=2.7.11.13; protein kinase C theta type; OTTHUMP00000019053;Background:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.;Description:Western Immunoblotting Reagents for Protein Kinase C Theta;Host Species:Rabbits;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;