Cat#:PA-3432F;Product Name:Western Immunoblotting Reagents for CHRNA4;Synonym:CHRNA4; cholinergic receptor, nicotinic, alpha 4; EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4; FLJ95812; neuronal acetylcholine receptor subunit alpha-4; OTTHUMP00000031784; cholinergic receptor, nicotinic, alpha polypeptide 4; neuronal nicotinic acetylcholine receptor alpha-4 subunit;Background:This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described.;Description:Western Immunoblotting Reagents for CHRNA4;Host Species:Rabbits;Species Reactivity:Human;Isotype:N/A;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;