Cat#:PA-641F;Product Name:Sheep Anti-Staphylococcal alpha Hemolysin Antibody;Synonym:Alpha hemolysin; Alpha-HL; Alpha-toxin; Hla; Hly; Staphylococcus alpha HL; Staphylococcus alpha toxin; Alpha-hemolysin; hly; hla; Staphylococcal alpha Hemolysin; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus; Staphylococcus aureus;Background:Staphylococcus aureus alpha Hemolysin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. The toxin self-assembles to form first, a nonlytic oligomeric intermediate, and then, a mushroom-shaped homoheptamer structure. Heptamer oligomerization and pore formation is required for lytic activity.;Description:Sheep Anti-Staphylococcal alpha Hemolysin Polyclonal Antibody;Host Species:Sheep;Species Reactivity:bacteria;Isotype:IgG1, kappa.;Application:ELISA;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Staphylococcus aureus alpha Hemolysin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. The toxin self-assembles to form first, a nonlytic oligomeric intermediate, and then, a mushroom-shaped homoheptamer structure. Heptamer oligomerization and pore formation is required for lytic activity.