Cat#:PA-1461F;Product Name:Sheep Anti-Human Receptor Associated Protein (RAP) Antibody;Synonym:LRPAP1; low density lipoprotein receptor-related protein associated protein 1; RAP; MRAP; A2RAP; HBP44; A2MRAP; MGC138272; alpha-2-macroglobulin receptor-associated protein; alpha-2-MRAP; OTTHUMP00000115346; lipoprotein receptor associated protein; Alpha-2-macroglobulin receptor-associated protein; Alpha-2-MRAP; low density lipoprotein-related protein-associated protein 1;Background:T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable), J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random addition of nucleotides by terminal deoxynucleotidyltransferase.;Description:Sheep Anti-Human Receptor Associated Protein (RAP) Polyclonal Antibody;Host Species:Sheep;Species Reactivity:Human;Isotype:IgG;Application:ELISA, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;