Cat#:PA-4083F;Product Name:Sheep Anti-Human Aldosterone Antibody;Synonym:Aldocorten; Aldocortene; Aldocortin; D-aldosterone; Elektrocortin; ELECTROCORTIN;LECTROCORTIN;REICHSTEIN X; ALDOCORTICOSTERONE;18-KETOCORTICOSTERONE; ALDOSTERONE;Background:Aldosterone is a hormone that increases the reabsorption of sodium ions and water and the release (secretion) of potassium ions in the collecting ducts and distal convoluted tubule of the kidneys' functional unit, the nephron. This increases blood volume and, therefore, increases blood pressure. Drugs that interfere with the secretion or action of aldosterone are in use as antihypertensives. One example is spironolactone, which lowers blood pressure by blocking the aldosterone receptor. Aldosterone is part of the renin-angiotensin system. Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland.;Description:Sheep Anti-Human Aldosterone Polyclonal Antibody;Host Species:Sheep;Species Reactivity:Human;Isotype:IgG3;Application:ELISA;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;