Cat#:PA-1646F;Product Name:Rat Anti-Mouse CD18 (LFA-1 Beta) Antibody;Synonym:2E6; LAD; Cd18; Lfa1; MF17; LCAMB; AI528527; Itgb2; integrin beta-2; Mac-1 beta; OTTMUSP00000021575; macrophage antigen-1 beta; complement receptor C3 subunit beta; lymphocyte function associated antigen 1; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;Background:The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.[1] In humans lack of CD18 causes Leukocyte Adhesion Deficiency, a disease defined by a lack of leukocyte extravasation from blood into tissues.;Description:Rat Anti-Mouse CD18 (LFA-1 Beta) Monoclonal Antibody;Host Species:Rat;Species Reactivity:Mouse;Clone#:C72/28;Isotype:IgG2a (Rat);Application:FCM, IP;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;