Cat#:PA-515F;Product Name:Rabbit Anti-SLC2A10 (a.a. 367-385) Antibody;Synonym:SLC2A10; solute carrier family 2 (facilitated glucose transporter), member 10; ATS; GLUT10; MGC126706; solute carrier family 2, facilitated glucose transporter member 10;Background:Glucose transporters (GLUT or SLC2A family) are a family of membrane proteins found in most mammalian cells. GLUTs are integral membrane proteins that contain 12 membrane-spanning helices with both the amino and carboxyl termini exposed on the cytoplasmic side of the plasma membrane. GLUT proteins transport glucose and related hexoses according to a model of alternate conformation, which predicts that the transporter exposes a single substrate binding site toward either the outside or the inside of the cell. Binding of glucose to one site provokes a conformational change associated with transport, and releases glucose to the other side of the membrane. The inner and outer glucose-binding sites are, it seems, located in transmembrane segments 9, 10, 11; also, the QLS motif located in the seventh transmembrane segment could be involved in the selection and affinity of transported substrate.;Description:Rabbit Anti-SLC2A10 (a.a. 367-385) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG2b;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;