Cat#:PA-458F;Product Name:Rabbit Anti-Mouse Stradb (a.a. 399-418) Antibody;Synonym:Stradb; STE20-related kinase adaptor beta; Papk; ILPIP; ILPIPA; Syradb; Als2cr2; D1Ucla2; PRO1038; AA792893; B830008M19; STE20-related kinase adapter protein beta; STRAD beta; OTTMUSP00000022732; pseudokinase ALS2CR2; ILP-interacting protein homolog; polyploidy associated protein kinase; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog; ILP-interacting protein homolog; Polyploidy-associated protein kinase; Pseudokinase ALS2CR2;Background:Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2, is connected to transferase/kinase activity and ATP binding, it has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1 converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.;Description:Rabbit Anti-Mouse Stradb (a.a. 399-418) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Mouse;Isotype:IgG1, kappa.;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;