Cat#:PA-888F;Product Name:Rabbit Anti-Mouse Plat Antibody;Synonym:Plat; plasminogen activator, tissue; tPA; AU020998; AW212668; D8Ertd2e; MGC18508; tissue-type plasminogen activator; t-plasminogen activator;Background:This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.;Description:Rabbit Anti-Mouse Plat Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Mouse;Application:ELISA, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;