Cat#:PA-131F;Product Name:Rabbit Anti-Human UNG Antibody;Synonym:UNG; uracil-DNA glycosylase; DGU; UDG; UNG1; UNG2; HIGM4; UNG15; DKFZp781L1143; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; Uracil-DNA glycosylase; EC=3.2.2.27; OTTHUMP00000240527; OTTHUMP00000240528; OTTHUMP00000240529; Uracil-DNA Glycosylase 2;Background:Uracil-DNA glycosylase, also known as UNG or UDG, is a human gene though orthologs exist ubiquitously among prokaryotes and eukaryotes and even in some DNA viruses. The first uracil DNA-glycosylase was isolated from Escherichia coli. The human gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2.;Description:Rabbit Anti-Human UNG Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;