Cat#:PA-284F;Product Name:Rabbit Anti-Human TNFSF12 Antibody;Synonym:TNFSF12; tumor necrosis factor (ligand) superfamily, member 12provided; APO3L; DR3LG; TWEAK; MGC20669; MGC129581; APO3 ligand; APO3/DR3 ligand; OTTHUMP00000135287; OTTHUMP00000205659; TNF-related WEAK inducer of apoptosis; APO 3 ligand; APO3 ligand; APO3L; CD255; DR3LG; HCG1991317; TNF12_HUMAN; TNFRS12a; UNQ181/PRO207;Background:The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.;Description:Rabbit Anti-Human TNFSF12 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;