Cat#:PA-649F;Product Name:Rabbit Anti-Human S100A1 Antibody;Synonym:S100; S100A; S100-alpha; S100A1; S100 protein, alpha polypeptide; protein S100-A1; S-100 protein subunit alpha; S100 calcium-binding protein A1; S-100 protein alpha chain;Background:S100 is a multigene family of low molecular weight (Mr between 9 000 and 13 000) Ca2+-binding proteins. The family comprises 19 members that are differentially expressed in a large number of cell types. Thus, S100B (previously S100β) is most abundant in glial cells of the central and peripheral nervous system, in melano-cytes, chondrocytes, and adipocytes, whereas S100A1 (previously S100A/S100α) is most abundant in cardio-myocytes, slow twitch skeletal muscle cells, salivary epithelial cells, and renal cells. Additionally, S100B is found in tumour cells and subpopulations of neurons, while S100A1 has also been detected in hippocampal neurons. S100A6 is expressed by fibroblasts and smooth and heart muscle cells. Members of the S100 family have been implicated in the Ca2+-dependent regulation of a variety of intracellular activities, e.g. protein phosphorylation, cell proliferation (including neoplastic transformation), and differentiation;Description:Rabbit Anti-Human S100A1 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;