Cat#:PA-708F;Product Name:Rabbit Anti-Human RNF7 (a.a. 102-113) Antibody;Synonym:RNF7; ring finger protein 7; SAG; ROC2; CKBBP1; sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2; RING-box protein 2; Rbx2; CKII beta-binding protein 1; RING finger protein 7; Regulator of cullins 2; Sensitive to apoptosis gene protein; RBX2; rbx2; OTTHUMP00000180644; OTTHUMP00000180645; regulator of cullins 2; zinc RING finger protein SAG; sensitive to apoptosis gene protein;Background:The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.;Description:Rabbit Anti-Human RNF7 (a.a. 102-113) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG2b;Application:ELISA, IP, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;