Cat#:PA-825F;Product Name:Rabbit Anti-Human PRKCB (a.a. 661-671) Antibody;Synonym:PRKCB; protein kinase C, beta; PKCB; PRKCB1; PRKCB2; MGC41878; PKC-beta; protein kinase C, beta 1; Protein kinase C beta type; PKC-B; PKC-beta; protein kinase C beta type; OTTHUMP00000162377; OTTHUMP00000162378; protein kinase C, beta 1 polypeptide;Background:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.;Description:Rabbit Anti-Human PRKCB (a.a. 661-671) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
PRKCB; protein kinase C, beta; PKCB; PRKCB1; PRKCB2; MGC41878; PKC-beta; protein kinase C, beta 1; Protein kinase C beta type; PKC-B; PKC-beta; protein kinase C beta type; OTTHUMP00000162377; OTTHUMP00000162378; protein kinase C, beta 1 polypeptide
Gene Introduction:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.