Cat#:PA-1062F;Product Name:Rabbit Anti-Human OPRK1 (a.a. 346-380) Antibody;Synonym:OPRK1; opioid receptor, kappa 1; KOR; OPRK; kappa-type opioid receptor; KOR-1; K-OR-1; OTTHUMP00000226313; OTTHUMP00000226316; kappa opioid receptor; Opiate receptor, kappa-1 Help top of page;Background:Three types of opioid receptors have been cloned: mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Most actions of exogenous opioids, such as morphine, are mediated through the µ-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception,neuroendocrine secretion and the immune response.;Description:Rabbit Anti-Human OPRK1 (a.a. 346-380) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:N/A;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
OPRK1; opioid receptor, kappa 1; KOR; OPRK; kappa-type opioid receptor; KOR-1; K-OR-1; OTTHUMP00000226313; OTTHUMP00000226316; kappa opioid receptor; Opiate receptor, kappa-1 Help top of page
Gene Introduction:
Three types of opioid receptors have been cloned: mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Most actions of exogenous opioids, such as morphine, are mediated through the µ-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception,neuroendocrine secretion and the immune response.