Cat#:PA-1089F;Product Name:Rabbit Anti-Human NPR2 (a.a. 288-302) Antibody;Synonym:NPR2; natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B); AMDM; ANPb; NPRB; ANPRB; GUC2B; NPRBi; GUCY2B; acromesomelic dysplasia, Maroteaux type; Atrial natriuretic peptide receptor type B; Atrial natriuretic peptide receptor 2; ANP-B; ANPR-B; NPR-B; GC-B; atrial natriuretic peptide receptor 2; OTTHUMP00000021345; guanylate cyclase B; atrial natriuretic peptide B-type receptor; atrial natriuretic peptide receptor type B.;Background:This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.;Description:Rabbit Anti-Human NPR2 (a.a. 288-302) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;