Cat#:PA-1186F;Product Name:Rabbit Anti-Human NLRP1 Antibody;Synonym:NLRP1; NLR family, pyrin domain containing 1; NAC; CARD7; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; KIAA0926; DEFCAP-L/S; DKFZp586O1822; NACHT, leucine rich repeat and PYD (pyrin domain) containing 1; NACHT, LRR and PYD domains-containing protein 1; Caspase recruitment domain-containing protein 7; Death effector filament-forming ced-4-like apoptosis protein; Nucleotide-binding domain and caspase recruitment domain; caspase recruitment domain protein 7; NACHT, LRR and PYD containing protein 1; NACHT, leucine rich repeat and PYD containing 1; caspase recruitment domain-containing protein 7; nucleotide-binding domain and caspase recruitment domain; death effector filament-forming Ced-4-like apoptosis protein; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1;Background:This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.;Description:Rabbit Anti-Human NLRP1 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG2b;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;