Cat#:PA-1674F;Product Name:Rabbit Anti-Human insulin receptor substrate 1 Antibody;Synonym:IRS1; insulin receptor substrate 1; HIRS-1; IRS-1; OTTHUMP00000164234;Background:Insulin receptor substrate (IRS) is an important ligand in the insulin response of human cells. IRS-1, for example, is an IRS protein which contains a phosphotyrosine binding-domain (PTB-domain). In addition, the insulin receptor contains a NPXpY domain. The PTB-domain binds the NPXpY domain. Thus, the insulin receptor binds IRS.;Description:Rabbit Anti-Human insulin receptor substrate 1 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG2a,k;Application:WB, IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Insulin receptor substrate (IRS) is an important ligand in the insulin response of human cells. IRS-1, for example, is an IRS protein which contains a phosphotyrosine binding-domain (PTB-domain). In addition, the insulin receptor contains a NPXpY domain. The PTB-domain binds the NPXpY domain. Thus, the insulin receptor binds IRS.