Cat#:PA-1728F;Product Name:Rabbit Anti-Human IL13 Antibody;Synonym:IL13; interleukin 13; ALRH; BHR1; P600; IL-13; MGC116786; MGC116788; MGC116789; Interleukin-13; OTTHUMP00000066048;Background:This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.;Description:Rabbit Anti-Human IL13 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG2a;Application:ELISA, Neut, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;