Cat#:PA-2340F;Product Name:Rabbit Anti-Human IBSP (a.a. 262-279) Antibody;Synonym:IBSP; integrin-binding sialoprotein; BSP; BNSP; SP-II; BSP-II; bone sialoprotein 2; OTTHUMP00000161175; bone sialoprotein II; cell-binding sialoprotein; Bone sialoprotein 2;Background:The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% ofthe noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophicchondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is thetrophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cellattachment through an RGD sequence that recognizes the vitronectin receptor.;Description:Rabbit Anti-Human IBSP (a.a. 262-279) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:EIA, FIA;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
IBSP; integrin-binding sialoprotein; BSP; BNSP; SP-II; BSP-II; bone sialoprotein 2; OTTHUMP00000161175; bone sialoprotein II; cell-binding sialoprotein; Bone sialoprotein 2
Gene Introduction:
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% ofthe noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophicchondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is thetrophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cellattachment through an RGD sequence that recognizes the vitronectin receptor.