Cat#:PA-2457F;Product Name:Rabbit Anti-Human HRK Antibody;Synonym:HRK; DP5; HARAKIRI; harakiri, BCL2 interacting protein (contains only BH3 domain); activator of apoptosis hara-kiri; DP5; activator of apoptosis Hrk; Neuronal death protein DP5; BCL2-interacting protein; BH3-interacting domain-containing protein 3; death protein 5; harakiri, BCL2-interacting protein (contains only BH3 domain); BID3;;Background:Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL;Description:Rabbit Anti-Human HRK Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;