Cat#:PA-3104F;Product Name:Rabbit Anti-Human EIF2S1 Antibody;Synonym:EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha; eukaryotic translation initiation factor 2 subunit 1; eIF-2-alpha; OTTHUMP00000028404; OTTHUMP00000218025; eukaryotic translation initiation factor 2 subunit alpha;Background:Eukaryotic translation initiation factor 2 subunit 1 is a protein that in humans is encoded by the EIF2S1 gene. Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.;Description:Rabbit Anti-Human EIF2S1 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:N/A;Application:WB, IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;