Cat#:PA-3180F;Product Name:Rabbit Anti-Human DRD3 (a.a. 2-10) Antibody;Synonym:D3DR; ETM1; FET1; MGC149204; MGC149205; dopamine receptor D3; DRD3; D(3) dopamine receptor; OTTHUMP00000214909; OTTHUMP00000214910; OTTHUMP00000214911; essential tremor 1; dopamine D3 receptor;Background:This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is expressed in phylogenetically older regions of the brain, suggesting that it plays a role in cognitive and emotional functions. It is a target for drugs which treat schizophrenia, drug addiction, and Parkinson disease. Alternative splicing of this gene results in multiple transcript variants that would encode different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).;Description:Rabbit Anti-Human DRD3 (a.a. 2-10) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1;Application:LF, Pr;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is expressed in phylogenetically older regions of the brain, suggesting that it plays a role in cognitive and emotional functions. It is a target for drugs which treat schizophrenia, drug addiction, and Parkinson disease. Alternative splicing of this gene results in multiple transcript variants that would encode different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).