Cat#:PA-3420F;Product Name:Rabbit Anti-Human CIDEC Antibody;Synonym:cell death-inducing DFFA-like effector c; CIDEC; FSP27; CIDE-3; FLJ20871; cell death activator CIDE-3; OTTHUMP00000158645; OTTHUMP00000207602; fat specific protein 27; Cell Death Inducing DFFA Like Effector C; Cell death inducing DFFA like effector protein C; Cell death-inducing DFFA-like effector protein C; CIDE3; CIDEC; CIDEC_HUMAN; FLJ20871; Fsp27; fat specific protein 27; Fat-specific protein FSP27 homolog; CIDEX;Background:This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified.;Description:Rabbit Anti-Human CIDEC Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
cell death-inducing DFFA-like effector c; CIDEC; FSP27; CIDE-3; FLJ20871; cell death activator CIDE-3; OTTHUMP00000158645; OTTHUMP00000207602; fat specific protein 27; Cell Death Inducing DFFA Like Effector C; Cell death inducing DFFA like effector protein C; Cell death-inducing DFFA-like effector protein C; CIDE3; CIDEC; CIDEC_HUMAN; FLJ20871; Fsp27; fat specific protein 27; Fat-specific protein FSP27 homolog; CIDEX
Gene Introduction:
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified.
Description:
Rabbit Anti-Human CIDEC Polyclonal Antibody
Host Species:
Rabbit
Species Reactivity:
Human
Application:
WB
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles